Can permanent filler be dissolved?
No. Only hyaluronic acid filler can be dissolved (with an enzyme). Permanent fillers — biopolymer, liquid silicone, PMMA and old semi-permanent products — cannot be dissolved and must be surgically removed.
What is biopolymer, and why is it a problem?
“Biopolymer” usually means injectable silicone or similar permanent substances, often injected into the buttocks. Over time it migrates, hardens and causes chronic inflammation, granulomas, pain and distortion — which is why removal is so often needed.
Can all of the filler be removed?
Not always completely. When biopolymer or silicone has spread widely through the tissue, removing every trace safely is not possible. The realistic goals are to remove as much as is safe, take out the worst granulomas, and relieve the symptoms — and you are told honestly what your case allows.
How is the filler removed?
By surgical excision — the encapsulated filler and the inflammatory granulomas are carefully cut out, under general anaesthesia. It is reconstructive surgery, planned individually for the area and the material involved.
Which areas do you treat most?
Most often the buttocks, where biopolymer and silicone injections are common, as well as the face and other areas of the body where permanent filler has caused problems.
Will my shape be restored?
The first priority is removing the material and relieving symptoms. Where volume or contour is lost, restoration — such as fat grafting or a lift — is planned as a second stage once the tissue has healed.
Is the pain and inflammation likely to improve?
For most patients, removing the material and the granulomas significantly relieves the chronic pain and inflammation it was causing. The degree of improvement depends on how much can be removed.
I had filler abroad and don’t know what it was — can you help?
Yes. Part of the assessment is examining the area — sometimes with imaging — to understand what is there and how it behaves, then planning removal accordingly. You do not need to know the exact product to be assessed.
Is permanent filler dangerous to health?
Beyond lumps and deformity, permanent fillers can cause recurring infections and chronic inflammation, and are associated with longer-term immune reactions. This is a further reason many patients choose to have them removed — assessed individually at consultation.
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Medically reviewed by Dr. Paulo Michels
Brazilian-trained plastic surgeon · 18+ years · ISAPS, ASPS, SBCP & EPSS member · advanced training in Germany & the USA · book author & international speaker · Elyzee Hospital, Abu Dhabi
Last updated July 2026